7 Comments
Jan 22Liked by David Kingsley, PhD

Superb analysis, David. Thank you for all of this information and your grounded analysis.

It's such a large drop in live birth rates post 40 years old in Table 1.

Expand full comment
author

Thanks, Nathan. This was an interesting one to put together! I am hoping to do a follow up in the near future about the use of iPSCs to produce Oocytes, i.e,. no need for egg isolation!

I agree, the drop in live birth rate is stark! It goes to show the importance that window.

Expand full comment

That'd be really interesting. I know next to nothing on that process, though I've worked with some colleagues who have been tied to a lab that primarily researches iPSCs in the context of embryology.

Expand full comment
Jan 22Liked by David Kingsley, PhD

I love these articles. They're so well done: both a thorough discussion of the technology and accessible to non-scientists.

I've been trying to figure out how to upgrade to a paid subscription, but on the "you're subscribed" page under "status" it just says "free subscriber," and there's no option for doing anything else. Am I doing it wrong?

Expand full comment
author

Thank you, Fager, I truly appreciate the encouragement. These articles take a lot of effort to put together and it's great to know that they are resonating with readers.

Regarding the subscription, I had not previously enabled paid subscriptions. But after some thought, I decided to enable the paid option for those who want to contribute. I think this feature may offer some exciting possibilities for new content.

While I do not want to paywall any content, I think it's important to provide an incentive for contributors. Let me know if you have any ideas!

P.S. Thank you for being the first to consider this new subscription level! Your support and engagement mean a lot.

Expand full comment

There's been recent talks about human genetic modification that could develop super soldiers. Do you think they could make genetic modification to allow for safer pregnancies or is it primarily dependent on the mother?

Expand full comment
author

Hopefully I am understanding correctly, but you are asking if genetic modifications could be made to the Embryo to make pregnancy safer. I'm going to guess the answer to this is yes, but I'm also going to assume they are not things you would necessarily want to perform.

Expand full comment